Since she was little, it's been drilled into Amy's head by her dad that monogamy isn't realistic. Now a magazine writer, Amy lives by that credo; enjoying what she feels is an uninhibited life free from stifling, boring romantic commitment, but in actuality, she's kind of in a rut. When she finds herself starting to fall for the subject of the new article she's writing, a charming and successful sports doctor named Aaron Conners; Amy starts to wonder...

After Peter gets engaged to the woman of his dreams, he realizes he has not one friend to serve as his best man. To rectify the situation, he goes on a series of man-dates before he meets Sydney Fife, with whom he instantly bonds. While Peter and Sydney become closer, his relationship with his fiancee begins to suffer, forcing him to choose between her or his new B.F.F.

Professor Klump finds romance with a lovely fellow geneticist. When his alter ego Buddy Love breaks out and threatens trouble, its up to the rest of the hefty Klump family to save the day.

Seth and Evan are accepting the fact that they will be going to different colleges in the fall. Now, it seems more imporant than ever that they go to a high school party, and achieve some of their long time goals. This includes, but is not limited to, losing their virginity with the girl of their dreams by getting them wasted and being their "regret hookup." Their awkward friend Fogell gets a fake ID, with just the name McLovin, and agrees to get...

Over the holidays, Ned, an overprotective but loving dad and his family visit his daughter at Stanford, where he meets his biggest nightmare: her well-meaning but socially awkward Silicon Valley billionaire boyfriend, Laird. The rivalry develops, and Ned's panic level goes through the roof when he finds himself lost in this glamorous high-tech world and learns that Laird is about to pop the question.