The story of defiant Southern farmer, Newt Knight, and his extraordinary armed rebellion against the Confederacy.

Once upon a time in the far away kingdom of Dor lived a brave and virtuous mouse with comically oversized ears who dreamt of becoming a knight. Banished from his home for having such lofty ambitions, Despereaux sets off on an amazing adventure with his good-hearted rat friend Roscuro. The two go on a very noble quest to rescue an endangered princess and save an entire kingdom from darkness.